Proposed Alterations in the Martini-Henry Rifle

Martini : the First Clinical

THE MAN HIS WORK THE HISTORICAL CONTEXT THE PAUL MARTINI FOUNDATION CONCLUSION REFERENCES In 1932, Paul Martini (figure 1), professor of medicine at the University of Bonn, published a monograph entitled Methodology of Therapeutic Investigation. In this slim volume of 69 pages Martini summarised his 3 years as professor of medicine in Berlin, and his experience of the scientific investigation o...

RIFLE is not RIFLE: on the comparability of results

Page 1 of 2 (page number not for citation purposes) In the consensus RIFLE criteria [1] of acute kidney injury (AKI) the thresholds given for serum creatinine (sCr) increase and glomerular filtration rate (GFR) decrease (Table 1) do not correspond [2]. Direct measurement of GFR in clinical practice is difficult, and values are more often estimated (eGFR) by the Cockroft-Gault equation or the Mo...

Perspective on the Martini model.

The Martini model, a coarse-grained force field for biomolecular simulations, has found a broad range of applications since its release a decade ago. Based on a building block principle, the model combines speed and versatility while maintaining chemical specificity. Here we review the current state of the model. We describe recent highlights as well as shortcomings, and our ideas on the furthe...

RIFLE is alive: long live RIFLE

Diagnosis and classification of acute kidney injury was addressed systematically only 8 years ago when the classification called RIFLE (acronym of Risk, Injury, Failure, Loss of function and End stage Kidney disease describing progressive severity of renal damage) was created. Since then, several studies have tried to apply, validate, criticize and modify this initial scheme: as a matter of fac...

[Air-rifle injuries of the eyes].